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0GOSR1_HUMAN*   SwissProt (?) | Description Local Annotation Link Reference
General Information
NameGOSR1
Description28 kda golgi snare protein (golgi snap receptor complex member 1) (28 kda cis-golgi snare p28) (gos-28).
SpeciesHomo sapiens (NCBI taxonomy ID: 9606)
GO0005485 v-SNARE activity (TAS)
0006891 intra-Golgi transport (TAS)

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schematic display of those terms with internal associations, click the node and browse the corresponding GO term
Domain Architecture (Details)
InterPro domains assigned to SynO:
A crucial step in membrane fusion is the formation of the SNARE complex in which conserved regions.alled SNARE motifs.rom individual SNAREs associate and twist to form the core complex.hich is an all-parallel coiled coil. The neuronal SNARE complex is a heterotrimer of vesicular (v-) SNARE VAMP-2 and the two target plasma membrane (t-) SNAREssyntaxin 1A and SNAP-25. It has been proposed that SNARE core complex formation proceeds like a zipper.eginning at themembrane-distal region and propagating toward themembrane-proximal end. SNARE complex formation is an energy-releasing process that may supply the required freeenergy for membrane fusion .This family includes the Golgi SNAP receptor (SNARE) complex protein.hich is involved in transport from the endoplasmic reticulum to the golgi apparatus and intra-golgi transport.nd the vesicle transport v-SNARE protein.hat mediates vesicle transport pathways through interaction with T-SNAREs on the target membrane.
  IPR007705:Vesicle transport v-SNARE
IPR007705:V-SNARE 
Evalue:-59.0315170288086 
Location:74-229
SequencesProtein: GOSR1_HUMAN (250 aa)
mRNA: NM_001007025 NM_004871
Local Annotation
Synapse Ontology
priming for exocytosis prepares the calcium-dependent release and may involve partial fusion process. The vesicles are primed and become responsive to calcium.
sdb:0120 priming  (Evidence:domains)
attachment of the vesicle filled with transmitters involves a specific interaction between the vesicle membrane and the presynaptic active zone.
sdb:0148 docking  (Evidence:domains)
KO assignmentNot mapped to KEGG
Loci Structure (Details)Loci index, Chromosomal location, Length, Possible relational loci clusterExon1: 20 residues, 25828551-25828608Exon2: 40 residues, 25832286-25832401Exon3: 31 residues, 25835357-25835445Exon4: 38 residues, 25835806-25835914Exon5: 32 residues, 25841269-25841361Exon6: 27 residues, 25843822-25843897Exon7: 12 residues, 25862023-25862053Exon8: 29 residues, 25871082-25871165Exon9: 1522 residues, 25873397-25877957Exon10: 2 residues, -Jump to GOSR1_HUMANExon1: 20 residues, 25828551-25828608Exon2: 42 residues, 25832286-25832407Exon3: 31 residues, 25835357-25835445Exon4: 38 residues, 25835806-25835914Exon5: 32 residues, 25841269-25841361Exon6: 27 residues, 25843822-25843897Exon7: 12 residues, 25862023-25862053Exon8: 29 residues, 25871082-25871165Exon9: 1522 residues, 25873397-25877957Exon10: 2 residues, -Jump to GOSR1_HUMAN  
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Loci Cluster (Details)Loci: 2994 25828551-25877957 ~-49K 15450(GOSR1)(+)Loci: 2995 26273058-26310335 ~-37K 15466(CENTA2)(+)Loci: 2996 26446242-26725609 ~-279K 15473(NF1)(+)Loci: 2997 26742767-26889352 ~-147K 15482(RAB11FIP4)(+)Loci: 4279 25549033-25586831 ~-38K 15444(SLC6A4)(-)Link out to UCSC