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0GLUC_HUMAN*   SwissProt (?) | Description Local Annotation Link Reference
General Information
NameGCG
DescriptionGlucagon precursor .
SpeciesHomo sapiens (NCBI taxonomy ID: 9606)
GO0005625 soluble fraction (TAS)
0005102 receptor binding (TAS)
0008283 cell proliferation (TAS)
0007631 feeding behavior (TAS)
0007186 G-protein coupled receptor protein signalin... (TAS)
0007165 signal transduction (TAS)

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schematic display of those terms with internal associations, click the node and browse the corresponding GO term
Domain Architecture (Details)
InterPro domains unassigned to SynO:
A number of polypeptidic hormones.ainly expressed in the intestine or the pancreas.elong to a group of structurally related peptides . Once such hormone.lucagon is widely distributed and produced in the alpha-cells of pancreatic islets . It affects glucose metabolism in the liver by inhibiting glycogen synthesis.timulating glycogenolysis and enchancing gluconeogenesis. It also increases mobilisation of glucose.ree fatty acids and ketone bodies.hich are metabolites produced in excess in diabetes mellitus. Glucagon is produced.ike other peptide hormones.s part of a larger precursor (preproglucagon).hich is cleaved to produce glucagon.lucagon-like protein I and glucagon-like protein II . The structure of glucagon itself is fully conserved in all known mammalian species . Other members of the structurally similar group include glicentin precursor.ecretin.astric inhibitory protein.asoactive intestinal peptide (VIP).realbumin.eptide HI-27 and growth hormone releasing factor.
  IPR000532:Glucagon/GIP/secretin/VIP
IPR000532:Hormone_2 
Evalue:-16.065502166748 
Location:53-80IPR000532:Hormone_2 
Evalue:-11.9208183288574 
Location:98-125IPR000532:Hormone_2 
Evalue:-9.82390880584717 
Location:146-173
SequencesProtein: GLUC_HUMAN (180 aa)
mRNA: NM_002054
Local Annotation
Synapse Ontology
Some have one process that touches a blood vessel while other processes touch neurons-- this is thought to aid neurons in obtaining nutrients; the processes of the astrocytes that touch the blood vessels are called astrocytic endfeet. Satellite cells, one kind of glias in PNS, are supportive cells in the PNS, found near PNS neuronal cell bodies.
sdb:0225 provide nutrition and maintenance of structure  (Evidence:keywords)
Microglias, one kind of glias in CNS, are responsible for removing most of the waste and cellular debris from the CNS
sdb:0267 removing metabolic mass  (Evidence:keywords)
KO assignmentNot mapped to KEGG
Loci Structure (Details)Loci index, Chromosomal location, Length, Possible relational loci clusterExon1: 165 residues, 162707634-162708126Exon2: 50 residues, 162708782-162708926Exon3: 48 residues, 162710295-162710433Exon4: 56 residues, 162712108-162712270Exon5: 35 residues, 162713842-162713943Exon6: 32 residues, 162716913-162717003Exon7: 2 residues, -Jump to GLUC_HUMAN  
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