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0GCP6_HUMAN*   SwissProt (?) | Description Local Annotation Link Reference
General Information
NameTUBGCP6
DescriptionGamma-tubulin complex component 6 (gcp-6).
SpeciesHomo sapiens (NCBI taxonomy ID: 9606)
GO0008274 gamma-tubulin ring complex (IDA)
0008017 microtubule binding (IDA)
0007020 microtubule nucleation (IDA)

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schematic display of those terms with internal associations, click the node and browse the corresponding GO term
Domain Architecture (Details)
InterPro domains unassigned to SynO:
Members of this family are spindle pole body (SBP) components such as Spc97.pc98 and gamma-tubulin. The SPB functions as the microtubule-organising centre in yeast.ith the microtubule cytoskeleton playing an essential role in chromosome segregation.ellular organisation and vesicle trafficking in eukaryotic cells. In most cells.he centrosome is the primary microtubule-organising centre that nucleates and organises microtubules. Gamma-tubulin localises to centrosomes and is required for microtubule nucleation. In Saccharomyces cerevisiae.amma-tubulin forms a stable complex with Spc97 and Spc98 .
  IPR007259:Spc97/Spc98
IPR007259:Spc97_Spc98 
Evalue:-160.769546508789 
Location:352-1697IPR006025:ZINC_PROTEASE 
Evalue:0 
Location:0-0
SequencesProtein: GCP6_HUMAN (1819 aa)
mRNA: NM_020461
Local Annotation
Synapse Ontology
microtubules of the presynaptic compartment function as the tracks for the intense traffic of organelles from cell body to axon terminals and vice versa. It is generally excluded from the presynaptic vesicle cluster.Microtubules do not directly regulate synapse morphology or function
sdb:0087 microtubules  (Evidence:keywords)
KO assignmentNot mapped to KEGG
Loci Structure (Details)Loci index, Chromosomal location, Length, Possible relational loci clusterExon1: 47 residues, 48998244-48998383Exon2: 68 residues, 48998473-48998673Exon3: 73 residues, 48998744-48998958Exon4: 46 residues, 48999043-48999176Exon5: 67 residues, 48999258-48999453Exon6: 49 residues, 48999623-48999765Exon7: 58 residues, 48999843-49000012Exon8: 51 residues, 49000199-49000347Exon9: 21 residues, 49000512-49000571Exon10: 543 residues, 49000806-49002430Exon11: 27 residues, 49002583-49002658Exon12: 48 residues, 49003009-49003148Exon13: 40 residues, 49004696-49004812Exon14: 31 residues, 49004887-49004976Exon15: 29 residues, 49005066-49005148Exon16: 52 residues, 49006349-49006499Exon17: 48 residues, 49006605-49006745Exon18: 32 residues, 49006842-49006934Exon19: 38 residues, 49007288-49007398Exon20: 28 residues, 49007554-49007633Exon21: 42 residues, 49008462-49008584Exon22: 60 residues, 49009959-49010133Exon23: 72 residues, 49013871-49014082Exon24: 56 residues, 49020759-49020923Exon25: 419 residues, 49024274-49025527Exon26: 2 residues, -Jump to GCP6_HUMAN  
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Loci Cluster (Details)Loci: 4580 49033457-49042216 ~-9K 25027(MAPK12)(-)Loci: 4581 49044269-49050906 ~-7K 25029(MAPK11)(-)Loci: 4582 49308864-49310838 ~-2K 25050(SCO2)(-)Loci: 4583 49311049-49315321 ~-4K 25051(ECGF1)(-)Loci: 4584 49354156-49363744 ~-10K 25054(CPT1B)(-)Loci: 4579 48998244-49025527 ~-27K 25025(TUBGCP6)(-)Link out to UCSC