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0GCP4_HUMAN*   SwissProt (?) | Description Local Annotation Link Reference
General Information
NameTUBGCP4
DescriptionGamma-tubulin complex component 4 (gcp-4) (hgcp4) (h76p) (hgrip76).
SpeciesHomo sapiens (NCBI taxonomy ID: 9606)
GO0005813 centrosome (TAS)
0008274 gamma-tubulin ring complex (NAS)
0015630 microtubule cytoskeleton (TAS)
0005200 structural constituent of cytoskeleton (NAS)
0007020 microtubule nucleation (NAS)
0006461 protein complex assembly (NAS)

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schematic display of those terms with internal associations, click the node and browse the corresponding GO term
Domain Architecture (Details)
InterPro domains unassigned to SynO:
Members of this family are spindle pole body (SBP) components such as Spc97.pc98 and gamma-tubulin. The SPB functions as the microtubule-organising centre in yeast.ith the microtubule cytoskeleton playing an essential role in chromosome segregation.ellular organisation and vesicle trafficking in eukaryotic cells. In most cells.he centrosome is the primary microtubule-organising centre that nucleates and organises microtubules. Gamma-tubulin localises to centrosomes and is required for microtubule nucleation. In Saccharomyces cerevisiae.amma-tubulin forms a stable complex with Spc97 and Spc98 .
  IPR007259:Spc97/Spc98
IPR007259:Spc97_Spc98 
Evalue:-228.142669677734 
Location:1-545
SequencesProtein: GCP4_HUMAN (667 aa)
mRNA: AK026551 NM_014444
Local Annotation
Synapse Ontology
microtubules of the presynaptic compartment function as the tracks for the intense traffic of organelles from cell body to axon terminals and vice versa. It is generally excluded from the presynaptic vesicle cluster.Microtubules do not directly regulate synapse morphology or function
sdb:0087 microtubules  (Evidence:keywords)
KO assignmentNot mapped to KEGG
Loci Structure (Details)Loci index, Chromosomal location, Length, Possible relational loci clusterExon1: 111 residues, 41450590-41450922Exon2: 45 residues, 41455587-41455716Exon3: 43 residues, 41455992-41456115Exon4: 20 residues, 41456503-41456557Exon5: 21 residues, 41457336-41457393Exon6: 28 residues, 41459573-41459653Exon7: 69 residues, 41462792-41462994Exon8: 57 residues, 41465280-41465446Exon9: 43 residues, 41465695-41465820Exon10: 19 residues, 41474596-41474647Exon11: 37 residues, 41475072-41475178Exon12: 38 residues, 41476703-41476811Exon13: 49 residues, 41477527-41477669Exon14: 61 residues, 41479533-41479711Exon15: 47 residues, 41481205-41481340Exon16: 41 residues, 41483172-41483289Exon17: 48 residues, 41483902-41484042Exon18: 281 residues, 41484691-41485530Exon19: 2 residues, -Jump to GCP4_HUMANExon1: 107 residues, 41450604-41450922Exon2: 45 residues, 41455587-41455716Exon3: 43 residues, 41455992-41456115Exon4: 20 residues, 41456503-41456557Exon5: 21 residues, 41457336-41457393Exon6: 28 residues, 41459573-41459653Exon7: 69 residues, 41462792-41462994Exon8: 57 residues, 41465280-41465446Exon9: 43 residues, 41465695-41465820Exon10: 19 residues, 41474596-41474647Exon11: 37 residues, 41475072-41475178Exon12: 38 residues, 41476703-41476811Exon13: 48 residues, 41477530-41477669Exon14: 61 residues, 41479533-41479711Exon15: 47 residues, 41481205-41481340Exon16: 41 residues, 41483172-41483289Exon17: 48 residues, 41483902-41484042Exon18: 281 residues, 41484691-41485530Exon19: 2 residues, -Jump to GCP4_HUMAN  
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Loci Cluster (Details)Loci: 4166 41276719-41300773 ~-24K 12193(EPB42)(-)Loci: 4167 41312647-41346347 ~-34K 12197(TGM5)(-)Loci: 2884 41450590-41485530 ~-35K 12206(TUBGCP4)(+)Loci: 2885 41672543-41678895 ~-6K 12220(CKMT1)(+)Loci: 2886 41772375-41778711 ~-6K 12228(CKMT1)(+)Loci: 2883 41213013-41264628 ~-52K 12186(+)Link out to UCSC