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0FAAH_HUMAN*   SwissProt (?) | Description Local Annotation Link Reference
General Information
NameFAAH
DescriptionFatty-acid amide hydrolase (ec 3.1.-.-) (oleamide hydrolase) (anandamide amidohydrolase).
SpeciesHomo sapiens (NCBI taxonomy ID: 9606)
GO0005626 insoluble fraction (TAS)
0005624 membrane fraction (TAS)
0004040 amidase activity (TAS)
0006631 fatty acid metabolism (TAS)

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schematic display of those terms with internal associations, click the node and browse the corresponding GO term
Domain Architecture (Details)
InterPro domains unassigned to SynO:
It has been shown that several enzymes from various prokaryotic andeukaryotic organisms which are involved in the hydrolysis of amides (amidases)are evolutionary related. All these enzymes contains in their central sectiona highly conserved region rich in glycine.erine.nd alanine residues.
  IPR000120:Amidase
IPR000120:Amidase 
Evalue:-156.10237121582 
Location:95-562
SequencesProtein: FAAH_HUMAN (579 aa)
mRNA: NM_001441
Local Annotation
Synapse Ontology
Microglias, one kind of glias in CNS, are responsible for removing most of the waste and cellular debris from the CNS
sdb:0267 removing metabolic mass  (Evidence:keywords)
KO assignmentK01175
  Level 3 annotation:
    
  Level 2 annotation:
    Other enzymes
Loci Structure (Details)Loci index, Chromosomal location, Length, Possible relational loci clusterExon1: 75 residues, 46632578-46632802Exon2: 40 residues, 46640349-46640463Exon3: 47 residues, 46643272-46643407Exon4: 46 residues, 46643630-46643764Exon5: 71 residues, 46643846-46644053Exon6: 15 residues, 46644296-46644337Exon7: 43 residues, 46644502-46644627Exon8: 44 residues, 46646717-46646843Exon9: 34 residues, 46647359-46647457Exon10: 35 residues, 46648656-46648756Exon11: 15 residues, 46649072-46649113Exon12: 15 residues, 46649870-46649910Exon13: 38 residues, 46650401-46650510Exon14: 50 residues, 46651333-46651479Exon15: 133 residues, 46651705-46652099Exon16: 2 residues, -Jump to FAAH_HUMAN  
Tune and view alternative isoforms
Loci Cluster (Details)Loci: 3799 46426941-46436685 ~-10K 1371(POMGNT1)(-)Loci: 2515 46632578-46652099 ~-20K 1383(FAAH)(+)Loci: 3800 46873299-46906615 ~-33K 1396(-)Loci: 2514 46041871-46274383 ~-233K 1363(MAST2)(+)Link out to UCSC