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0DYL2_HUMAN*   SwissProt (?) | Description Local Annotation Link Reference
General Information
NameDLC2
DescriptionDynein light chain 2, cytoplasmic.
SpeciesHomo sapiens (NCBI taxonomy ID: 9606)
GO0030286 dynein complex (ISS)
0016459 myosin (ISS)
0005515 protein binding (ISS)
0046907 intracellular transport (ISS)

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schematic display of those terms with internal associations, click the node and browse the corresponding GO term
Domain Architecture (Details)
InterPro domains unassigned to SynO:
Dynein is a multisubunit microtubule-dependent motor enzyme that acts as the force generating protein of eukaryotic cilia and flagella. The cytoplasmic isoform of dynein acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. Dynein is composed of a number of ATP-binding large subunits (see ).ntermediate size subunits and small subunits. Among the small subunits.here is a family of highly conserved proteins which make up this family .
  IPR001372:Dynein light chain, type 1
IPR001372:Dynein_light 
Evalue:-66.8239059448242 
Location:1-89
SequencesProtein: DYL2_HUMAN (89 aa)
mRNA: NM_080677
Local Annotation
Synapse Ontology
microtubules of the presynaptic compartment function as the tracks for the intense traffic of organelles from cell body to axon terminals and vice versa. It is generally excluded from the presynaptic vesicle cluster.Microtubules do not directly regulate synapse morphology or function
sdb:0087 microtubules  (Evidence:keywords)
KO assignmentNot mapped to KEGG
Loci Structure (Details)Loci index, Chromosomal location, Length, Possible relational loci clusterExon1: 83 residues, 53515797-53516043Exon2: 49 residues, 53519441-53519582Exon3: 105 residues, 53521501-53521810Exon4: 2 residues, -Jump to DYL2_HUMAN  
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Loci Cluster (Details)Loci: 3025 53515797-53521810 ~-6K 16281(DLC2)(+)Loci: 4304 53733592-53760477 ~-27K 16290(BZRAP1)(-)Loci: 4305 53852527-53920744 ~-68K 16295(-)Loci: 4306 53952614-53964410 ~-12K 16299(-)Loci: 4303 53435861-53439592 ~-4K 16279(SFRS1)(-)Link out to UCSC