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0DYL1_HUMAN*   SwissProt (?) | Description Local Annotation Link Reference
General Information
DescriptionDynein light chain 1, cytoplasmic (8 kda dynein light chain) (dlc8) (protein inhibitor of neuronal nitric oxide synthase) (pin).
SpeciesHomo sapiens (NCBI taxonomy ID: 9606)
Domain Architecture (Details)
InterPro domains unassigned to SynO:
Dynein is a multisubunit microtubule-dependent motor enzyme that acts as the force generating protein of eukaryotic cilia and flagella. The cytoplasmic isoform of dynein acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. Dynein is composed of a number of ATP-binding large subunits (see ).ntermediate size subunits and small subunits. Among the small is a family of highly conserved proteins which make up this family .
  IPR001372:Dynein light chain, type 1
SequencesProtein: DYL1_HUMAN (89 aa)
mRNA: NM_001037494
Local Annotation
Synapse Ontology
microtubules of the presynaptic compartment function as the tracks for the intense traffic of organelles from cell body to axon terminals and vice versa. It is generally excluded from the presynaptic vesicle cluster.Microtubules do not directly regulate synapse morphology or function
sdb:0087 microtubules  (Evidence:keywords)
KO assignmentNot mapped to KEGG
Loci Structure (Details)Loci index, Chromosomal location, Length, Possible relational loci clusterExon1: 83 residues, 119392042-119392290Exon2: 48 residues, 119418601-119418739Exon3: 142 residues, 119420258-119420680Exon4: 2 residues, -Jump to DYL1_HUMAN  
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Loci Cluster (Details)Loci: 4079 119017288-119038982 ~-22K 9812(RAB35)(-)Loci: 4080 119132639-119187892 ~-55K 9820(PXN)(-)Loci: 2793 119360286-119362912 ~-3K 9830(COX6A1)(+)Loci: 4081 119383853-119391941 ~-8K 9835(SFRS9)(-)Loci: 2794 119392042-119420680 ~-29K 9836(DNCL1)(+)Loci: 2795 119572753-119589508 ~-17K 9842(CABP1)(+)Loci: 4078 118607977-118799478 ~-192K 9809(CIT)(-)Link out to UCSC