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0DLG7_HUMAN*   SwissProt (?) | Description Local Annotation Link Reference
General Information
NameDLG7
DescriptionDiscs large homolog 7 (hepatoma up-regulated protein) (hurp).
SpeciesHomo sapiens (NCBI taxonomy ID: 9606)
GON/A
Domain Architecture (Details)
InterPro domains unassigned to SynO:
The protein called postsynaptic density (PSD) is a specialized submembranous structure within which synaptic membrane proteins are linked to cytoskeleton and signalling proteins. Guanylate-kinase-associated protein (PSD-95/synapse-associated protein 90) is one of the major components of PSD.nd functions as a scaffold protein for various ion channels and associated signalling molecules.
  IPR005026:Guanylate-kinase-associated protein
IPR005026:GKAP 
Evalue:-4.88605642318726 
Location:310-607
SequencesProtein: DLG7_HUMAN (846 aa)
mRNA: NM_014750
Local Annotation
Synapse Ontology
Calcium release from RyR (Ryanodine Receptor) in the SR (Sarcoplasmic Reticulum) is activated by the calcium induced-calcium-release
sdb:0325 RyR-CICR  (Evidence:keywords)
KO assignmentNot mapped to KEGG
Loci Structure (Details)Loci index, Chromosomal location, Length, Possible relational loci clusterExon1: 115 residues, 54684600-54684944Exon2: 18 residues, 54687269-54687319Exon3: 84 residues, 54688165-54688412Exon4: 21 residues, 54689060-54689118Exon5: 65 residues, 54691087-54691277Exon6: 75 residues, 54694992-54695212Exon7: 37 residues, 54699441-54699546Exon8: 55 residues, 54705869-54706030Exon9: 30 residues, 54707172-54707258Exon10: 44 residues, 54711816-54711943Exon11: 43 residues, 54712364-54712489Exon12: 93 residues, 54713532-54713807Exon13: 25 residues, 54716099-54716170Exon14: 43 residues, 54717126-54717249Exon15: 30 residues, 54717683-54717768Exon16: 23 residues, 54718840-54718903Exon17: 66 residues, 54720030-54720224Exon18: 81 residues, 54725412-54725651Exon19: 74 residues, 54727933-54728149Exon20: 2 residues, -Jump to DLG7_HUMAN  
Tune and view alternative isoforms
Loci Cluster (Details)Loci: 4133 54684600-54728149 ~-44K 11182(DLG7)(-)Loci: 2839 54807831-54890080 ~-82K 11183(FBXO34)(+)Loci: 2840 55116787-55221047 ~-104K 11187(KTN1)(+)Loci: 4132 54378475-54439292 ~-61K 11172(GCH1)(-)Link out to UCSC