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0DHC24_HUMAN*   SwissProt (?) | Description Local Annotation Link Reference
General Information
NameDHCR24
Description24-dehydrocholesterol reductase precursor (ec 1.3.1.-) (3-beta- hydroxysterol delta-24-reductase) (seladin-1) (diminuto/dwarf1 homolog).
SpeciesHomo sapiens (NCBI taxonomy ID: 9606)
GON/A
Domain Architecture (Details)
InterPro domains unassigned to SynO:
Various enzymes use FAD as a co-factor.ost of these enzymes are oxygen-dependent oxidoreductases.ontaining a covalently bound FAD group which is attached to a histidine via an 8-alpha-(N3-histidyl)-riboflavin linkage. One of the enzymes Vanillyl-alcohol oxidase (VAO. has a solved structure.he alignment includes the FAD binding site.alled the PP-loop.etween residues 99-110 . The FAD molecule is covalently bound in the known structure.owever the residue that links to the FAD is not in the alignment. VAO catalyses the oxidation of a wide variety of substrates.anging from aromatic amines to 4-alkylphenols.
  IPR006094:FAD linked oxidase, N-terminal
IPR006094:FAD_binding_4 
Evalue:-13.3767509460449 
Location:114-203
SequencesProtein: DHC24_HUMAN (516 aa)
mRNA: NM_014762
Local Annotation
Synapse Ontology
introduce the substructure of the synapse and the location where the molecule can be seen. It will contain all the constructive special organelle and molecule we known.
sdb:0001 Structure/Biochemistry of synapse  (Evidence:keywords)
KO assignmentK00224
  Level 3 annotation:
    
  Level 2 annotation:
    Propanoate metabolism
    Tryptophan metabolism
    1
    1
    1-Trichloro-2
    2-bis(4-chlorophenyl)ethane (DDT) degradation
Loci Structure (Details)Loci index, Chromosomal location, Length, Possible relational loci clusterExon1: 921 residues, 55087887-55090647Exon2: 61 residues, 55091694-55091873Exon3: 68 residues, 55092297-55092495Exon4: 50 residues, 55103563-55103707Exon5: 90 residues, 55109610-55109874Exon6: 41 residues, 55113353-55113472Exon7: 37 residues, 55114202-55114308Exon8: 54 residues, 55121878-55122034Exon9: 116 residues, 55125149-55125493Exon10: 2 residues, -Jump to DHC24_HUMAN  
Tune and view alternative isoforms
Loci Cluster (Details)Loci: 3805 55087887-55125493 ~-38K 1573(DHCR24)(-)Loci: 2521 55277807-55303111 ~-25K 1577(PCSK9)(+)Loci: 2520 54786488-54873005 ~-87K 1560(ACOT11)(+)Link out to UCSC