SynDB Home Page
SynDB Home Page
Browse
Search
Download
Help
People
links

blue bulletSynDB protein details  


Parse error: syntax error, unexpected T_VARIABLE in /home/kongl/syndb/www/sdb_nats.php on line 52
0DGUOK_HUMAN*   SwissProt (?) | Description Local Annotation Link Reference
General Information
NameDGUOK
DescriptionDeoxyguanosine kinase, mitochondrial precursor (ec 2.7.1.113) (dgk).
SpeciesHomo sapiens (NCBI taxonomy ID: 9606)
GO0005739 mitochondrion (TAS)
0004138 deoxyguanosine kinase activity (TAS)
0008617 guanosine metabolism (TAS)

Warning: fopen(/home/kongl/syndb/www/temp/1724752126.dot) [function.fopen]: failed to open stream: Permission denied in /home/kongl/syndb/www/sdb_pro.php on line 269

Warning: fwrite(): supplied argument is not a valid stream resource in /home/kongl/syndb/www/sdb_pro.php on line 270

Warning: fwrite(): supplied argument is not a valid stream resource in /home/kongl/syndb/www/sdb_pro.php on line 271

Warning: fwrite(): supplied argument is not a valid stream resource in /home/kongl/syndb/www/sdb_pro.php on line 272

Warning: fwrite(): supplied argument is not a valid stream resource in /home/kongl/syndb/www/sdb_pro.php on line 273

Warning: fwrite(): supplied argument is not a valid stream resource in /home/kongl/syndb/www/sdb_pro.php on line 274

Warning: fwrite(): supplied argument is not a valid stream resource in /home/kongl/syndb/www/sdb_pro.php on line 299

Warning: fclose(): supplied argument is not a valid stream resource in /home/kongl/syndb/www/sdb_pro.php on line 300
schematic display of those terms with internal associations, click the node and browse the corresponding GO term
Domain Architecture (Details)
InterPro domains unassigned to SynO:
This family consists of various deoxynucleoside kinases including cytidine ().uanosine ().denosine () and thymidine kinase (.hich also phosphorylates deoxyuridine and deoxycytosine. These enzymes catalyse the production of deoxynucleotide 5-monophosphate from a deoxynucleoside.sing ATP and yielding ADP in the process.
  IPR002624:Deoxynucleoside kinase
IPR002624:dNK 
Evalue:-75.6777801513672 
Location:110-267
SequencesProtein: DGUOK_HUMAN (277 aa)
mRNA: NM_080916
Local Annotation
Synapse Ontology
transport of vesicles in the presynaptic neuron
sdb:0017 Mobilization: synapsins, CAM kinase I  (Evidence:keywords)
mitochondria are frequently observed in the vicinity of the synaptic vesicle clusters, in agreement with the ATP requirement of several steps of the vesicle cycle.
sdb:0118 mitochondria  (Evidence:keywords)
KO assignmentK00904
  Level 3 annotation:
    deoxyguanosine kinase
  Level 2 annotation:
    Purine metabolism
Loci Structure (Details)Loci index, Chromosomal location, Length, Possible relational loci clusterExon1: 76 residues, 74007460-74007687Exon2: 39 residues, 74019544-74019657Exon3: 64 residues, 74027353-74027541Exon4: 51 residues, 74031219-74031367Exon5: 40 residues, 74037759-74037875Exon6: 35 residues, 74038780-74038880Exon7: 85 residues, 74039344-74039594Exon8: 2 residues, -Jump to DGUOK_HUMAN  
Tune and view alternative isoforms
Loci Cluster (Details)Loci: 3171 73973600-74000287 ~-27K 20655(ACTG2)(+)Loci: 3172 74007460-74039594 ~-32K 20656(DGUOK)(+)Loci: 4449 74441789-74461472 ~-20K 20675(DCTN1)(-)Loci: 4450 74613453-74634593 ~-21K 20704(LOXL3)(-)Loci: 3170 73909654-73943518 ~-34K 20654(STAMBP)(+)Link out to UCSC