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0DCTN4_HUMAN*   SwissProt (?) | Description Local Annotation Link Reference
General Information
NameDCTN4
DescriptionDynactin subunit 4 (dynactin subunit p62).
SpeciesHomo sapiens (NCBI taxonomy ID: 9606)
GO0005813 centrosome (TAS)
0005737 cytoplasm (TAS)
0005634 nucleus (TAS)

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schematic display of those terms with internal associations, click the node and browse the corresponding GO term
Domain Architecture (Details)
InterPro domains unassigned to SynO:
Dynactin is a multi-subunit complex and a required cofactor for most.r all.f the cellular processes powered by the microtubule-based motor cytoplasmic dynein. p62 binds directly to the Arp1 subunit of dynactin .
  IPR008603:Dynactin p62
IPR008603:Dynactin_p62 
Evalue:-283.795867919922 
Location:23-448
SequencesProtein: DCTN4_HUMAN (460 aa)
mRNA: NM_016221
Local Annotation
Synapse Ontology
microtubules of the presynaptic compartment function as the tracks for the intense traffic of organelles from cell body to axon terminals and vice versa. It is generally excluded from the presynaptic vesicle cluster.Microtubules do not directly regulate synapse morphology or function
sdb:0087 microtubules  (Evidence:keywords)
KO assignmentNot mapped to KEGG
Loci Structure (Details)Loci index, Chromosomal location, Length, Possible relational loci clusterExon1: 872 residues, 150068502-150071117Exon2: 34 residues, 150075319-150075417Exon3: 38 residues, 150078030-150078138Exon4: 20 residues, 150079470-150079525Exon5: 26 residues, 150082661-150082735Exon6: 38 residues, 150090385-150090495Exon7: 39 residues, 150090798-150090911Exon8: 26 residues, 150091170-150091244Exon9: 38 residues, 150093122-150093230Exon10: 16 residues, 150101868-150101912Exon11: 61 residues, 150113233-150113412Exon12: 25 residues, 150116171-150116242Exon13: 54 residues, 150118613-150118769Exon14: 2 residues, -Jump to DCTN4_HUMAN  
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Loci Cluster (Details)Loci: 4743 149563423-149649529 ~-86K 29756(CAMK2A)(-)Loci: 4744 149656101-149662641 ~-7K 29760(ARSI)(-)Loci: 3502 149960834-150012089 ~-51K 29771(SYNPO)(+)Loci: 4745 150068502-150118769 ~-50K 29777(DCTN4)(-)Loci: 3501 149549712-149570827 ~-21K 29755(SLC6A7)(+)Link out to UCSC