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0DACH1_HUMAN*   SwissProt (?) | Description Local Annotation Link Reference
General Information
NameDACH1
DescriptionDachshund homolog 1 (dach1).
SpeciesHomo sapiens (NCBI taxonomy ID: 9606)
GO0005515 protein binding (IPI)
0007456 eye morphogenesis (sensu Endopterygota) (TAS)

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schematic display of those terms with internal associations, click the node and browse the corresponding GO term
Domain Architecture (Details)
InterPro domains unassigned to SynO:
The c-ski proto-oncogene has been shown to influence proliferation.orphological transformation and myogenic differentiation . It may play a role in terminal differentiation of skeletal muscle cells but not in the determination of cells to the myogenic lineage. Sno. Ski proto-oncogene homologue.s expressed in two isoforms and plays a role in the response to proliferation stimuli.
  IPR003380:Transforming protein Ski
A putative DNA-binding domain with a conserved structure is found in several different protein families. The core structure of the domain consists of a three-helical fold that is architecturally similar to that of the "winged-helix" fold.ut is topologically distinct. Representatives of this domain can be found in domains B1 and B5 from the beta subunit of phenylalanine-tRNA synthetases .he C-terminal region of the DNA/RPA-binding domain of the DNA excision repair factor XPA .he N-terminal domain of the transcriptional activators BmrR and MtaN .he most conserved domain of the retinal development protein Dachshund .nd the DNA-binding domain of the gpNU1 subunit from the bacteriophage lambda viral packing protein terminase .
  IPR009061:Putative DNA binding
IPR003380:Ski_Sno 
Evalue:-79.4436950683594 
Location:167-282
SequencesProtein: DACH1_HUMAN (758 aa)
mRNA: NM_080759
Local Annotation
Synapse Ontology
transport of vesicles in the presynaptic neuron
sdb:0017 Mobilization: synapsins, CAM kinase I  (Evidence:keywords)
calcium-regulated transcription factor
sdb:0215 calcium-regulated transcription factor  (Evidence:keywords)
KO assignmentNot mapped to KEGG
Loci Structure (Details)Loci index, Chromosomal location, Length, Possible relational loci clusterExon1: 910 residues, 70910098-70912825Exon2: 25 residues, 70947273-70947342Exon3: 50 residues, 70947838-70947982Exon4: 51 residues, 70951301-70951449Exon5: 52 residues, 70961129-70961281Exon6: 47 residues, 71029156-71029291Exon7: 47 residues, 71031952-71032088Exon8: 59 residues, 71044972-71045145Exon9: 56 residues, 71102688-71102850Exon10: 40 residues, 71153927-71154043Exon11: 427 residues, 71338054-71339331Exon12: 2 residues, -Jump to DACH1_HUMAN  
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