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0CX6A1_HUMAN*   SwissProt (?) | Description Local Annotation Link Reference
General Information
NameCOX6A1
DescriptionCytochrome c oxidase polypeptide via-liver, mitochondrial precursor (ec 1.9.3.1).
SpeciesHomo sapiens (NCBI taxonomy ID: 9606)
GO0006091 generation of precursor metabolites and energy (TAS)
Domain Architecture (Details)
InterPro domains unassigned to SynO:
Cytochrome c oxidase () is an oligomeric enzymatic complex which is a component of the respiratory chain complex and is involved in the transfer of electrons from cytochrome c to oxygen . In eukaryotes this enzyme complex is located in the mitochondrial inner membrane; in aerobic prokaryotes it is found in the plasma membrane. In eukaryotes.n addition to the three large subunits..I and III.hat form the catalytic center of the enzyme complex.here are a variable number of small polypeptidic subunits. One of these subunits is known as VIa in vertebrates and fungi. Mammals have two tissue-specific isoforms of VIa. liver and a heart form. Only one form is found in fish .
  IPR001349:Cytochrome c oxidase, subunit VIa
IPR001349:COX6A 
Evalue:-58.3187599182129 
Location:24-109
SequencesProtein: CX6A1_HUMAN (109 aa)
mRNA: NM_004373
Local Annotation
Synapse Ontology
mitochondria are frequently observed in the vicinity of the synaptic vesicle clusters, in agreement with the ATP requirement of several steps of the vesicle cycle.
sdb:0118 mitochondria  (Evidence:keywords)
KO assignmentNot mapped to KEGG
Loci Structure (Details)Loci index, Chromosomal location, Length, Possible relational loci clusterExon1: 44 residues, 119360286-119360415Exon2: 49 residues, 119360564-119360707Exon3: 93 residues, 119362639-119362912Exon4: 2 residues, -Jump to CX6A1_HUMAN  
Tune and view alternative isoforms
Loci Cluster (Details)Loci: 4079 119017288-119038982 ~-22K 9812(RAB35)(-)Loci: 4080 119132639-119187892 ~-55K 9820(PXN)(-)Loci: 2793 119360286-119362912 ~-3K 9830(COX6A1)(+)Loci: 4081 119383853-119391941 ~-8K 9835(SFRS9)(-)Loci: 2794 119392042-119420680 ~-29K 9836(DNCL1)(+)Loci: 2795 119572753-119589508 ~-17K 9842(CABP1)(+)Loci: 4078 118607977-118799478 ~-192K 9809(CIT)(-)Link out to UCSC