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0CU005_HUMAN*   SwissProt (?) | Description Local Annotation Link Reference
General Information
DescriptionProtein c21orf5.
SpeciesHomo sapiens (NCBI taxonomy ID: 9606)
GO0007275 development (NAS)
Domain Architecture (Details)
InterPro domains unassigned to SynO:
DopA is the founding member of the Dopey family and is required for correct cell morphology and spatiotemporal organisation of multicellular structures in the filamentous fungus Aspergillus nidulans. DopA homologues are found in mammals. Saccharomyces cerevisiae DOP1 is essential for viability and.ffects cellular morphogenesis .
  IPR007249:Dopey, N-terminal
SequencesProtein: CU005_HUMAN (2298 aa)
mRNA: NM_005128
Local Annotation
Synapse Ontology
Calcium release from RyR (Ryanodine Receptor) in the SR (Sarcoplasmic Reticulum) is activated by the calcium induced-calcium-release
sdb:0325 RyR-CICR  (Evidence:keywords)
KO assignmentNot mapped to KEGG
Loci Structure (Details)Loci index, Chromosomal location, Length, Possible relational loci clusterExon1: 18 residues, 36458708-36458761Exon2: 56 residues, 36458875-36459039Exon3: 62 residues, 36493237-36493419Exon4: 59 residues, 36494498-36494669Exon5: 65 residues, 36502882-36503072Exon6: 35 residues, 36505720-36505819Exon7: 43 residues, 36506141-36506265Exon8: 38 residues, 36508248-36508358Exon9: 40 residues, 36508609-36508724Exon10: 42 residues, 36513539-36513660Exon11: 42 residues, 36517398-36517518Exon12: 36 residues, 36519732-36519835Exon13: 66 residues, 36521853-36522045Exon14: 230 residues, 36524617-36525302Exon15: 92 residues, 36526971-36527243Exon16: 53 residues, 36531429-36531582Exon17: 35 residues, 36532768-36532869Exon18: 65 residues, 36533932-36534123Exon19: 545 residues, 36539215-36540845Exon20: 39 residues, 36541684-36541796Exon21: 65 residues, 36542547-36542736Exon22: 43 residues, 36545329-36545452Exon23: 48 residues, 36547939-36548077Exon24: 20 residues, 36554844-36554900Exon25: 37 residues, 36557713-36557818Exon26: 24 residues, 36557915-36557982Exon27: 50 residues, 36564180-36564325Exon28: 28 residues, 36571188-36571268Exon29: 38 residues, 36572142-36572252Exon30: 51 residues, 36572376-36572523Exon31: 22 residues, 36574452-36574514Exon32: 45 residues, 36575650-36575779Exon33: 47 residues, 36582181-36582318Exon34: 20 residues, 36582923-36582979Exon35: 56 residues, 36583212-36583374Exon36: 45 residues, 36586271-36586401Exon37: 320 residues, 36587487-36588441Exon38: 2 residues, -Jump to CU005_HUMAN  
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