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0CPT1A_HUMAN*   SwissProt (?) | Description Local Annotation Link Reference
General Information
NameCPT1A
DescriptionCarnitine o-palmitoyltransferase i, mitochondrial liver isoform (ec 2.3.1.21) (cpt i) (cpti-l) (carnitine palmitoyltransferase 1a).
SpeciesHomo sapiens (NCBI taxonomy ID: 9606)
GO0005739 mitochondrion (TAS)
0004095 carnitine O-palmitoyltransferase activity (TAS)
0006635 fatty acid beta-oxidation (TAS)

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schematic display of those terms with internal associations, click the node and browse the corresponding GO term
Domain Architecture (Details)
InterPro domains assigned to SynO:
A number of eukaryotic acetyltransferases can.n the basis of sequence similarities.e grouped together into a family. These enzymes include choline o-acetyltransferase ().n enzyme that catalyzes the biosynthesis of the neurotransmitter acetylcholine ; carnitine o-acetyltransferase () ; peroxisomal carnitine octanoyltransferase (). fatty acid beta-oxidation pathway enzyme which is involved in the transport of medium-chain acyl-coenzyme As from peroxisome to mitochondria ; mitochondrial carnitine palmitoyltransferases I and II () (CPT).nzymes involved in fatty acid metabolism and transport ; and Mycoplasma pneumoniae putative acetyltransferase C09_orf600.
  IPR000542:Acyltransferase ChoActase/COT/CPT
IPR000542:Carn_acyltransf 
Evalue:-1e+125 
Location:170-763
SequencesProtein: CPT1A_HUMAN (773 aa)
mRNA: NM_001876
Local Annotation
Synapse Ontology
transmitter inactivated by its enzyme etc.
sdb:0141 extracellular metabolism  (Evidence:domains)
?
sdb:0328 transmitters release and endocytosis  (Evidence:domains)
KO assignmentK00636
  Level 3 annotation:
    carnitine O-palmitoyltransferase
  Level 2 annotation:
    Fatty acid metabolism
    Adipocytokine signaling pathway
Loci Structure (Details)Loci index, Chromosomal location, Length, Possible relational loci clusterExon1: 211 residues, 68281144-68281774Exon2: 33 residues, 68283612-68283705Exon3: 40 residues, 68284268-68284382Exon4: 53 residues, 68285578-68285731Exon5: 47 residues, 68286670-68286805Exon6: 57 residues, 68297308-68297473Exon7: 41 residues, 68299359-68299476Exon8: 37 residues, 68304683-68304789Exon9: 65 residues, 68305814-68306003Exon10: 67 residues, 68308858-68309054Exon11: 31 residues, 68317358-68317446Exon12: 38 residues, 68318847-68318955Exon13: 28 residues, 68320899-68320977Exon14: 48 residues, 68323261-68323399Exon15: 36 residues, 68328043-68328145Exon16: 59 residues, 68331510-68331682Exon17: 48 residues, 68336480-68336620Exon18: 53 residues, 68339377-68339531Exon19: 23 residues, 68365818-68365881Exon20: 2 residues, -Jump to CPT1A_HUMAN  
Tune and view alternative isoforms
Loci Cluster (Details)Loci: 2691 68427947-68464635 ~-37K 7282(IGHMBP2)(+)Loci: 3967 68281144-68365881 ~-85K 7280(CPT1A)(-)Link out to UCSC