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0COX83_HUMAN*   SwissProt (?) | Description Local Annotation Link Reference
General Information
DescriptionCytochrome c oxidase polypeptide viii isoform 3, mitochondrial precursor (ec (cytochrome c oxidase subunit 8-3) (cox viii- 3).
SpeciesHomo sapiens (NCBI taxonomy ID: 9606)
Domain Architecture (Details)
InterPro domains unassigned to SynO:
Cytochrome c oxidase () is an oligomeric enzymatic complex which is a component of the respiratory chain complex and is involved in the transfer of electrons from cytochrome c to oxygen . In eukaryotes this enzyme complex is located in the mitochondrial inner membrane; in aerobic prokaryotes it is found in the plasma membrane. In eukaryotes.n addition to the three large subunits..I and III.hat form the catalytic center of the enzyme are a variable number of small polypeptidic subunits.This family is composed of cytochrome c oxidase subunit VIII.
  IPR003205:Cytochrome oxidase c, subunit VIII
SequencesProtein: COX83_HUMAN (72 aa)
mRNA: NM_182971
Local Annotation
Synapse Ontology
mitochondria are frequently observed in the vicinity of the synaptic vesicle clusters, in agreement with the ATP requirement of several steps of the vesicle cycle.
sdb:0118 mitochondria  (Evidence:keywords)
KO assignmentK02273
  Level 3 annotation:
    cytochrome c oxidase subunit VIII
  Level 2 annotation:
    Oxidative phosphorylation
Loci Structure (Details)Loci index, Chromosomal location, Length, Possible relational loci clusterExon1: 69 residues, 92883289-92883493Exon2: 111 residues, 92884126-92884453Exon3: 2 residues, -Jump to COX83_HUMAN  
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Loci Cluster (Details)Loci: 4149 93257136-93324519 ~-67K 11665(PRIMA1)(-)Loci: 2860 92883289-92884453 ~-1K 11664(COX8C)(+)Link out to UCSC