SynDB Home Page
SynDB Home Page
Browse
Search
Download
Help
People
links

blue bulletSynDB protein details  


Parse error: syntax error, unexpected T_VARIABLE in /home/kongl/syndb/www/sdb_nats.php on line 52
0CLAT_HUMAN*   SwissProt (?) | Description Local Annotation Link Reference
General Information
NameCHAT
DescriptionCholine o-acetyltransferase (ec 2.3.1.6) (choactase) (choline acetylase) (chat).
SpeciesHomo sapiens (NCBI taxonomy ID: 9606)
GO0005737 cytoplasm (TAS)
0005634 nucleus (TAS)

Warning: fopen(/home/kongl/syndb/www/temp/456480068.dot) [function.fopen]: failed to open stream: Permission denied in /home/kongl/syndb/www/sdb_pro.php on line 269

Warning: fwrite(): supplied argument is not a valid stream resource in /home/kongl/syndb/www/sdb_pro.php on line 270

Warning: fwrite(): supplied argument is not a valid stream resource in /home/kongl/syndb/www/sdb_pro.php on line 271

Warning: fwrite(): supplied argument is not a valid stream resource in /home/kongl/syndb/www/sdb_pro.php on line 272

Warning: fwrite(): supplied argument is not a valid stream resource in /home/kongl/syndb/www/sdb_pro.php on line 273

Warning: fwrite(): supplied argument is not a valid stream resource in /home/kongl/syndb/www/sdb_pro.php on line 274

Warning: fwrite(): supplied argument is not a valid stream resource in /home/kongl/syndb/www/sdb_pro.php on line 299

Warning: fclose(): supplied argument is not a valid stream resource in /home/kongl/syndb/www/sdb_pro.php on line 300
schematic display of those terms with internal associations, click the node and browse the corresponding GO term
Domain Architecture (Details)
InterPro domains assigned to SynO:
A number of eukaryotic acetyltransferases can.n the basis of sequence similarities.e grouped together into a family. These enzymes include choline o-acetyltransferase ().n enzyme that catalyzes the biosynthesis of the neurotransmitter acetylcholine ; carnitine o-acetyltransferase () ; peroxisomal carnitine octanoyltransferase (). fatty acid beta-oxidation pathway enzyme which is involved in the transport of medium-chain acyl-coenzyme As from peroxisome to mitochondria ; mitochondrial carnitine palmitoyltransferases I and II () (CPT).nzymes involved in fatty acid metabolism and transport ; and Mycoplasma pneumoniae putative acetyltransferase C09_orf600.
  IPR000542:Acyltransferase ChoActase/COT/CPT
IPR000542:Carn_acyltransf 
Evalue:-1e+125 
Location:130-720
SequencesProtein: CLAT_HUMAN (748 aa)
mRNA: AF305908 NM_020549
Local Annotation
Synapse Ontology
introduce the substructure of the synapse and the location where the molecule can be seen. It will contain all the constructive special organelle and molecule we known.
sdb:0001 Structure/Biochemistry of synapse  (Evidence:keywords,domains)
transmitter inactivated by its enzyme etc.
sdb:0141 extracellular metabolism  (Evidence:keywords,domains)
?
sdb:0328 transmitters release and endocytosis  (Evidence:keywords,domains)
KO assignmentK00623
  Level 3 annotation:
    choline O-acetyltransferase
  Level 2 annotation:
    Glycerophospholipid metabolism
Loci Structure (Details)Loci index, Chromosomal location, Length, Possible relational loci clusterExon1: 156 residues, 50492061-50492527Exon2: 35 residues, 50494553-50494654Exon3: 66 residues, 50497776-50497968Exon4: 41 residues, 50498546-50498665Exon5: 20 residues, 50500148-50500202Exon6: 62 residues, 50503524-50503705Exon7: 61 residues, 50505659-50505837Exon8: 58 residues, 50524556-50524726Exon9: 35 residues, 50526558-50526659Exon10: 45 residues, 50527559-50527688Exon11: 43 residues, 50529935-50530058Exon12: 49 residues, 50533146-50533288Exon13: 23 residues, 50533437-50533500Exon14: 48 residues, 50540696-50540834Exon15: 111 residues, 50542828-50543156Exon16: 2 residues, -Jump to CLAT_HUMANExon1: 147 residues, 50492088-50492527Exon2: 25 residues, 50494074-50494144Exon3: 35 residues, 50494553-50494654Exon4: 66 residues, 50497776-50497968Exon5: 41 residues, 50498546-50498665Exon6: 20 residues, 50500148-50500202Exon7: 62 residues, 50503524-50503705Exon8: 61 residues, 50505659-50505837Exon9: 58 residues, 50524556-50524726Exon10: 35 residues, 50526558-50526659Exon11: 45 residues, 50527559-50527688Exon12: 43 residues, 50529935-50530058Exon13: 49 residues, 50533146-50533288Exon14: 23 residues, 50533437-50533500Exon15: 48 residues, 50540696-50540834Exon16: 111 residues, 50542828-50543156Exon17: 2 residues, -Jump to CLAT_HUMAN  
Tune and view alternative isoforms
Loci Cluster (Details)Loci: 2614 50488352-50490771 ~-2K 4893(SLC18A3)(+)Loci: 2615 50492061-50543156 ~-51K 4895(CHAT)(+)Loci: 3890 50336714-50417078 ~-80K 4890(ERCC6)(-)Link out to UCSC