SynDB Home Page
SynDB Home Page
Browse
Search
Download
Help
People
links

blue bulletSynDB protein details  


Parse error: syntax error, unexpected T_VARIABLE in /home/kongl/syndb/www/sdb_nats.php on line 52
0CHSTE_HUMAN*   SwissProt (?) | Description Local Annotation Link Reference
General Information
NameD4ST1
DescriptionCarbohydrate sulfotransferase d4st1 (ec 2.8.2.-) (dermatan 4- sulfotransferase 1) (d4st-1) (hd4st).
SpeciesHomo sapiens (NCBI taxonomy ID: 9606)
GO0016021 integral to membrane (ISS)
0001537 N-acetylgalactosamine 4-O-sulfotransferase ... (ISS)
0042301 phosphate binding (ISS)
0050655 dermatan sulfate proteoglycan metabolism (ISS)

Warning: fopen(/home/kongl/syndb/www/temp/296739521.dot) [function.fopen]: failed to open stream: Permission denied in /home/kongl/syndb/www/sdb_pro.php on line 269

Warning: fwrite(): supplied argument is not a valid stream resource in /home/kongl/syndb/www/sdb_pro.php on line 270

Warning: fwrite(): supplied argument is not a valid stream resource in /home/kongl/syndb/www/sdb_pro.php on line 271

Warning: fwrite(): supplied argument is not a valid stream resource in /home/kongl/syndb/www/sdb_pro.php on line 272

Warning: fwrite(): supplied argument is not a valid stream resource in /home/kongl/syndb/www/sdb_pro.php on line 273

Warning: fwrite(): supplied argument is not a valid stream resource in /home/kongl/syndb/www/sdb_pro.php on line 274

Warning: fwrite(): supplied argument is not a valid stream resource in /home/kongl/syndb/www/sdb_pro.php on line 299

Warning: fclose(): supplied argument is not a valid stream resource in /home/kongl/syndb/www/sdb_pro.php on line 300
schematic display of those terms with internal associations, click the node and browse the corresponding GO term
Domain Architecture (Details)
InterPro domains unassigned to SynO:
Chondroitin 4-sulphotransferase catalyses the transfer of sulphate to the C-4 position of N-acetylgalactosamine in chondroitin and desulphated dermatan sulphate but did not form 4.-di-O-sulphated N-acetylgalactosamine when chondroitin sulphate C was used as an acceptor. This suggests that 4-O-sulphation at N-acetylgalactosamine may precede epimerization of glucuronic acid to iduronic acid during dermatan sulphate biosynthesis. HNK-1 and other Golgi-associated sulphotransferases share homologous sequences including the RDP motif.
  IPR005331:Chondroitin 4-O-sulfotransferase
IPR005331:Sulfotransfer_2 
Evalue:-174 
Location:64-370
SequencesProtein: CHSTE_HUMAN (376 aa)
mRNA: NM_130468
Local Annotation
Synapse Ontology
Calcium release from RyR (Ryanodine Receptor) in the SR (Sarcoplasmic Reticulum) is activated by the calcium induced-calcium-release
sdb:0325 RyR-CICR  (Evidence:keywords)
KO assignmentK08105
  Level 3 annotation:
    dermatan 4-sulfotransferase 1
  Level 2 annotation:
    Chondroitin sulfate biosynthesis
Loci Structure (Details)Loci index, Chromosomal location, Length, Possible relational loci clusterExon1: 714 residues, 38550504-38552645Exon2: 2 residues, -Jump to CHSTE_HUMAN  
Tune and view alternative isoforms
Loci Cluster (Details)Loci: 2873 38484977-38498355 ~-13K 12090(IVD)(+)Loci: 2874 38550504-38552645 ~-2K 12093(D4ST1)(+)Loci: 2875 38673738-38743829 ~-70K 12099(CASC5)(+)Loci: 2876 38843576-38847203 ~-4K 12107(GCHFR)(+)Loci: 2877 38973919-38983464 ~-10K 12116(VPS18)(+)Loci: 4163 38367401-38387330 ~-20K 12082(PLCB2)(-)Link out to UCSC