SynDB Home Page
SynDB Home Page
Browse
Search
Download
Help
People
links

blue bulletSynDB protein details  


Parse error: syntax error, unexpected T_VARIABLE in /home/kongl/syndb/www/sdb_nats.php on line 52
0CENPF_HUMAN*   SwissProt (?) | Description Local Annotation Link Reference
General Information
NameCENPF
DescriptionCenp-f kinetochore protein (centromere protein f) (mitosin) (ah antigen).
SpeciesHomo sapiens (NCBI taxonomy ID: 9606)
GO0000776 kinetochore (TAS)
0005634 nucleus (TAS)
0005819 spindle (TAS)
0000067 DNA replication and chromosome cycle (TAS)
0007088 regulation of mitosis (TAS)

Warning: fopen(/home/kongl/syndb/www/temp/899191669.dot) [function.fopen]: failed to open stream: Permission denied in /home/kongl/syndb/www/sdb_pro.php on line 269

Warning: fwrite(): supplied argument is not a valid stream resource in /home/kongl/syndb/www/sdb_pro.php on line 270

Warning: fwrite(): supplied argument is not a valid stream resource in /home/kongl/syndb/www/sdb_pro.php on line 271

Warning: fwrite(): supplied argument is not a valid stream resource in /home/kongl/syndb/www/sdb_pro.php on line 272

Warning: fwrite(): supplied argument is not a valid stream resource in /home/kongl/syndb/www/sdb_pro.php on line 273

Warning: fwrite(): supplied argument is not a valid stream resource in /home/kongl/syndb/www/sdb_pro.php on line 274

Warning: fwrite(): supplied argument is not a valid stream resource in /home/kongl/syndb/www/sdb_pro.php on line 299

Warning: fclose(): supplied argument is not a valid stream resource in /home/kongl/syndb/www/sdb_pro.php on line 300
schematic display of those terms with internal associations, click the node and browse the corresponding GO term
Domain Architecture (Details)
InterPro domains unassigned to SynO:
ATP:guanido phosphotransferases are a family of structurally and functionally related enzymes .hat reversibly catalyze the transfer of phosphate between ATP and various phosphogens. The enzymes belonging to this family include glycocyamine kinase ().hich catalyzes the transfer of phosphate from ATP to guanidoacetate; arginine kinase ().hich catalyzes the transfer of phosphate from ATP to arginine; taurocyamine kinase ().n annelid-specific enzyme that catalyzes the transfer of phosphate from ATP to taurocyamine; lombricine kinase ().n annelid-specific enzyme that catalyzes the transfer of phosphate from ATP to lombricine; Smc74. cercaria-specific enzyme from Schistosoma mansoni ; and creatine kinase () (CK) which plays an important role in energy metabolism of vertebrates. It catalyzes the reversible transfer of high energy phosphate from ATP to creatine.enerating phosphocreatine and ADP. There are at least four different.ut very closely related.orms of CK. Two isozymes. (muscle) and B (brain).re cytosolic.hile the other two are mitochondrial. In sea urchin there is a flagellar isozyme.hich consists of the triplication of a CK-domain. A cysteine residue is implicated in the catalytic activity of these enzymes and the region around this active site residue is highly conserved.
  IPR000749:ATP:guanido phosphotransferase
IPR000749:ATP-gua_Ptrans 
Evalue:0 
Location:2307-2398
SequencesProtein: CENPF_HUMAN (3210 aa)
mRNA: NM_016343
Local Annotation
Synapse Ontology
microtubules of the presynaptic compartment function as the tracks for the intense traffic of organelles from cell body to axon terminals and vice versa. It is generally excluded from the presynaptic vesicle cluster.Microtubules do not directly regulate synapse morphology or function
sdb:0087 microtubules  (Evidence:keywords)
KO assignmentNot mapped to KEGG
Loci Structure (Details)Loci index, Chromosomal location, Length, Possible relational loci clusterExon1: 45 residues, 212843154-212843287Exon2: 69 residues, 212853679-212853882Exon3: 67 residues, 212854797-212854994Exon4: 42 residues, 212858538-212858660Exon5: 32 residues, 212859094-212859186Exon6: 99 residues, 212860620-212860912Exon7: 69 residues, 212862044-212862247Exon8: 44 residues, 212869011-212869137Exon9: 45 residues, 212870499-212870628Exon10: 43 residues, 212872445-212872568Exon11: 47 residues, 212877831-212877967Exon12: 1136 residues, 212879886-212883290Exon13: 950 residues, 212884522-212887366Exon14: 53 residues, 212888640-212888793Exon15: 61 residues, 212891675-212891852Exon16: 56 residues, 212892793-212892955Exon17: 56 residues, 212895206-212895369Exon18: 161 residues, 212896898-212897375Exon19: 61 residues, 212898815-212898994Exon20: 328 residues, 212903556-212904535Exon21: 2 residues, -Jump to CENPF_HUMAN  
Tune and view alternative isoforms