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0CD6_HUMAN*   SwissProt (?) | Description Local Annotation Link Reference
General Information
NameCD6
DescriptionT-cell differentiation antigen cd6 precursor (t12) (tp120).
SpeciesHomo sapiens (NCBI taxonomy ID: 9606)
GO0009986 cell surface (IEP)
0005887 integral to plasma membrane (TAS)

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schematic display of those terms with internal associations, click the node and browse the corresponding GO term
Domain Architecture (Details)
InterPro domains unassigned to SynO:
The egg peptide speract receptor is a transmembrane glycoprotein . Other members of this family include the macrophagescavenger receptor type I (a membrane glycoprotein implicated in the pathologicdeposition of cholesterol in arterial walls during artherogenesis).n enteropeptidaseand T-cell surface glycoprotein CD5 (may act as a receptor in regulating T-cellproliferation).
  IPR001190:Speract/scavenger receptor
IPR001190:SR 
Evalue:-51.0132282657338 
Location:161-260IPR001190:SRCR 
Evalue:-37.8860549926758 
Location:268-361IPR001190:SRCR 
Evalue:-30.4317989349365 
Location:48-156
SequencesProtein: CD6_HUMAN (668 aa)
mRNA: NM_006725
Local Annotation
Synapse Ontology
Calcium release from RyR (Ryanodine Receptor) in the SR (Sarcoplasmic Reticulum) is activated by the calcium induced-calcium-release
sdb:0325 RyR-CICR  (Evidence:keywords)
KO assignmentK06456
  Level 3 annotation:
    CD6 antigen
  Level 2 annotation:
    CAM ligands
    CD molecules
Loci Structure (Details)Loci index, Chromosomal location, Length, Possible relational loci clusterExon1: 72 residues, 60495749-60495962Exon2: 25 residues, 60530621-60530690Exon3: 119 residues, 60531607-60531958Exon4: 106 residues, 60532581-60532893Exon5: 103 residues, 60533619-60533922Exon6: 24 residues, 60535117-60535183Exon7: 49 residues, 60537470-60537611Exon8: 34 residues, 60537966-60538062Exon9: 43 residues, 60539760-60539883Exon10: 26 residues, 60541526-60541598Exon11: 87 residues, 60541806-60542061Exon12: 37 residues, 60542336-60542441Exon13: 375 residues, 60543301-60544422Exon14: 2 residues, -Jump to CD6_HUMAN  
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