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0BSN_HUMAN*   SwissProt (?) | Description Local Annotation Link Reference
General Information
NameBSN
DescriptionBassoon protein (zinc-finger protein 231).
SpeciesHomo sapiens (NCBI taxonomy ID: 9606)
GO0005634 nucleus (TAS)
0007268 synaptic transmission (TAS)

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schematic display of those terms with internal associations, click the node and browse the corresponding GO term
Domain Architecture (Details)
InterPro domains unassigned to SynO:
This (predicted) Zinc finger is found in the bassoon and piccolo proteins (e.g. ). There are eight conserved cysteines.uggesting that it coordinates two zinc ligands.
  IPR008899:Zinc finger, piccolo-type
Zinc finger domains (ZnFs) are common.elatively small protein motifs that fold around one or more zinc ions. In addition to their role as a DNA-binding module.nFs have recently been shown to mediate protein:protein and protein:lipid interactions. There are at least 14 different classes of Zn fingers.hich differ in the nature and arrangement of their zinc-binding residues .The FYVE zinc finger domain is conserved from yeast to man.nd is named after four proteins that it has been found in: Fab1.OTB/ZK632.12.ac1.nd EEA1. It functions in the membrane recruitment of cytosolic proteins by binding to phosphatidylinositol 3-phosphate (PI3P).hich is found mainly on endosomes .The plant homeodomain (PHD) zinc finger domain has a C4HC3-type motif.nd is widely distributed in eukaryotes.eing found in many chromatin regulatory factors .Both the FYVE and the PHD zinc finger motifs display strikingly similar dimetal(zinc)-bound alpha+beta folds.The SSF signature in this entry is currently under review. Please be aware that some of the protein hits may be false positives.
  IPR011011:Zinc finger, FYVE/PHD-type
IPR008899:zf-piccolo 
Evalue:-36.4685211181641 
Location:460-520IPR008899:zf-piccolo 
Evalue:-35.6382713317871 
Location:165-225
SequencesProtein: BSN_HUMAN (3925 aa)
mRNA: NM_003458
Local Annotation
Synapse Ontology
introduce the substructure of the synapse and the location where the molecule can be seen. It will contain all the constructive special organelle and molecule we known.
sdb:0001 Structure/Biochemistry of synapse  (Evidence:keywords)
all
sdb:0004 Presynaptic compartment  (Evidence:keywords)
attachment of the vesicle filled with transmitters involves a specific interaction between the vesicle membrane and the presynaptic active zone.
sdb:0148 docking  (Evidence:keywords)
the plasma membrane is thicked into an active zone to which several synaptic vesicles are attached.
sdb:0151 active zone  (Evidence:keywords)
?
sdb:0223 transmitter release  (Evidence:keywords)
?
sdb:0328 transmitters release and endocytosis  (Evidence:keywords)
KO assignmentNot mapped to KEGG
Loci Structure (Details)Loci index, Chromosomal location, Length, Possible relational loci clusterExon1: 113 residues, 49566925-49567263Exon2: 138 residues, 49637411-49637820Exon3: 297 residues, 49654704-49655589Exon4: 158 residues, 49663048-49663516Exon5: 2220 residues, 49663979-49670633Exon6: 694 residues, 49672922-49674999Exon7: 265 residues, 49675312-49676103Exon8: 35 residues, 49676223-49676323Exon9: 46 residues, 49676859-49676991Exon10: 20 residues, 49677235-49677290Exon11: 32 residues, 49677665-49677755Exon12: 1318 residues, 49680026-49683976Exon13: 2 residues, -Jump to BSN_HUMAN  
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Loci Cluster (Details)Loci: 4601 48530128-48569231 ~-39K 25651(PFKFB4)(-)Loci: 4602 48611435-48622102 ~-11K 25656(UQCRC1)(-)Loci: 4603 48637834-48684985 ~-47K 25658(CELSR3)(-)Loci: 4604 48686283-48698338 ~-12K 25669(NCKIPSD)(-)Loci: 4605 48762098-48860265 ~-98K 25672(-)Loci: 4606 49133551-49145603 ~-12K 25699(LAMB2)(-)Loci: 4607 49429215-49435016 ~-6K 25713(AMT)(-)Loci: 3354 49566925-49683976 ~-117K 25718(BSN)(+)Loci: 4608 49921309-49942261 ~-21K 25739(-)Loci: 4609 50330243-50333903 ~-4K 25774(HYAL2)(-)Loci: 4600 48420266-48441746 ~-21K 25634(PLXNB1)(-)Link out to UCSC