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0BACH_HUMAN*   SwissProt (?) | Description Local Annotation Link Reference
General Information
NameACOT7
DescriptionCytosolic acyl coenzyme a thioester hydrolase (ec 3.1.2.2) (long chain acyl-coa thioester hydrolase) (cte-ii) (cte-iia) (brain acyl-coa hydrolase) (acyl-coa thioesterase 7).
SpeciesHomo sapiens (NCBI taxonomy ID: 9606)
GO0005737 cytoplasm (TAS)
0000062 acyl-CoA binding (TAS)
0003824 catalytic activity (TAS)
0006629 lipid metabolism (TAS)

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schematic display of those terms with internal associations, click the node and browse the corresponding GO term
Domain Architecture (Details)
InterPro domains unassigned to SynO:
This family contains a wide variety of enzymes.rincipally thioesterases. This family includes 4HBT () which catalyses the final step in the biosynthesis of 4-hydroxybenzoate from 4-chlorobenzoate in the soil dwelling microbe Pseudomonas CBS-3. This family includes various cytosolic long-chain acyl-CoA thioester hydrolases. Long-chain acyl-CoA hydrolases hydrolyse palmitoyl-CoA to CoA and palmitate.hey also catalyse the hydrolysis of other long chain fatty acyl-CoA thioesters.
  IPR006683:Thioesterase superfamily
IPR006683:4HBT 
Evalue:-18.8860569000244 
Location:242-319IPR006683:4HBT 
Evalue:-17.4685211181641 
Location:68-151
SequencesProtein: BACH_HUMAN (380 aa)
mRNA: NM_181864
Local Annotation
Synapse Ontology
the generation of action potential at soma of neurons.
sdb:0313 generation of AP at soma  (Evidence:keywords)
Calcium release from RyR (Ryanodine Receptor) in the SR (Sarcoplasmic Reticulum) is activated by the calcium induced-calcium-release
sdb:0325 RyR-CICR  (Evidence:keywords)
KO assignmentK01068
  Level 3 annotation:
    palmitoyl-CoA hydrolase
  Level 2 annotation:
    Other lipid metabolism
Loci Structure (Details)Loci index, Chromosomal location, Length, Possible relational loci clusterExon1: 142 residues, 6246919-6247342Exon2: 63 residues, 6263748-6263933Exon3: 41 residues, 6277510-6277627Exon4: 31 residues, 6301138-6301225Exon5: 40 residues, 6309945-6310060Exon6: 32 residues, 6316123-6316215Exon7: 54 residues, 6322079-6322236Exon8: 41 residues, 6332395-6332513Exon9: 112 residues, 6368140-6368470Exon10: 2 residues, -Jump to BACH_HUMAN  
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Loci Cluster (Details)Loci: 2476 6538020-6562403 ~-24K 272(+)Loci: 3767 6246919-6368470 ~-122K 244(ACOT7)(-)Link out to UCSC