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0B4GT4_HUMAN*   SwissProt (?) | Description Local Annotation Link Reference
General Information
NameB4GALT4
DescriptionBeta-1,4-galactosyltransferase 4 (ec 2.4.1.-) (beta-1,4-galtase 4) (beta4gal-t4) (b4gal-t4) (udp-galactose:beta-n-acetylglucosamine beta- 1,4-galactosyltransferase 4) (udp-gal:beta-glcnac beta-1,4- galactosyltransferase 4) .
SpeciesHomo sapiens (NCBI taxonomy ID: 9606)
GO0016021 integral to membrane (TAS)
0008378 galactosyltransferase activity (TAS)
0006643 membrane lipid metabolism (TAS)

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Domain Architecture (Details)
InterPro domains unassigned to SynO:
This is a family of galactosyltransferases from a wide range of metazoa with three related galactosyltransferase activities; all three of which are possessed by one sequence in some cases. The three functions are N-acetyllactosamine synthase (); beta-N-acetylglucosaminyl-glycopeptide beta-1.-galactosyltransferase (); and lactose synthase (). Note that N-acetyllactosamine synthase is a component of lactose synthase along with alpha-lactalbumin.n the absence of alpha-lactalbumin N-acetyllactosamine synthase is used.
  IPR003859:Metazoa galactosyltransferase
IPR003859:Galactosyl_T_2 
Evalue:-190.21467590332 
Location:77-344
SequencesProtein: B4GT4_HUMAN (344 aa)
mRNA: NM_212543
Local Annotation
Synapse Ontology
Calcium release from RyR (Ryanodine Receptor) in the SR (Sarcoplasmic Reticulum) is activated by the calcium induced-calcium-release
sdb:0325 RyR-CICR  (Evidence:keywords)
KO assignmentK00723
  Level 3 annotation:
    N-acetyllactosamine synthase
  Level 2 annotation:
    Other enzymes
K07969
  Level 3 annotation:
    beta-1,4-galactosyltransferase 4
  Level 2 annotation:
    Blood group glycolipid biosynthesis - neo-lactoseries
Loci Structure (Details)Loci index, Chromosomal location, Length, Possible relational loci clusterExon1: 312 residues, 120413285-120414218Exon2: 37 residues, 120417776-120417881Exon3: 43 residues, 120420186-120420309Exon4: 64 residues, 120425594-120425782Exon5: 79 residues, 120428345-120428578Exon6: 134 residues, 120431383-120431781Exon7: 29 residues, 120436681-120436764Exon8: 74 residues, 120438389-120438607Exon9: 20 residues, 120442386-120442442Exon10: 2 residues, -Jump to B4GT4_HUMAN  
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Loci Cluster (Details)Loci: 3370 120700057-120725813 ~-26K 26250(+)Loci: 4628 120413285-120442442 ~-29K 26244(B4GALT4)(-)Link out to UCSC