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0ATX2_HUMAN*   SwissProt (?) | Description Local Annotation Link Reference
General Information
NameATXN2
DescriptionAtaxin-2 (spinocerebellar ataxia type 2 protein) (trinucleotide repeat-containing gene 13 protein).
SpeciesHomo sapiens (NCBI taxonomy ID: 9606)
GO0005737 cytoplasm (TAS)
0005634 nucleus (TAS)

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schematic display of those terms with internal associations, click the node and browse the corresponding GO term
Domain Architecture (Details)
InterPro domains unassigned to SynO:
This entry represents a conserved region approximately 250 residues long located towards the C terminus of eukaryotic ataxin-2. Ataxin-2 is a protein of unknown function.ithin which expansion of a polyglutamine tract (due to expansion of unstable CAG repeats in the coding region of the SCA2 gene) causes spinocerebellar ataxia type 2 (SCA2). late-onset neurodegenerative disorder . The expanded polyglutamine repeat in ataxin-2 causes disruption of the normal morphology of the Golgi complex and increased incidence of cell death . Ataxin-2 is predicted to consist of mostly non-globular domains .
  IPR009604:Ataxin-2, N-terminal
This entry represents a conserved region approximately 250 residues long located towards the C terminus of eukaryotic ataxin-2. Ataxin-2 is a protein of unknown function.ithin which expansion of a polyglutamine tract (due to expansion of unstable CAG repeats in the coding region of the SCA2 gene) causes spinocerebellar ataxia type 2 (SCA2). late-onset neurodegenerative disorder . The expanded polyglutamine repeat in ataxin-2 causes disruption of the normal morphology of the Golgi complex and increased incidence of cell death . Ataxin-2 is predicted to consist of mostly non-globular domains .
  IPR009818:Ataxin-2, C-terminal
IPR009604:Ataxin-2_N 
Evalue:-65.7447280883789 
Location:353-475IPR009818:PAM2 
Evalue:-5.53760194778442 
Location:908-925
SequencesProtein: ATX2_HUMAN (1312 aa)
mRNA: NM_002973
Local Annotation
Synapse Ontology
introduce the substructure of the synapse and the location where the molecule can be seen. It will contain all the constructive special organelle and molecule we known.
sdb:0001 Structure/Biochemistry of synapse  (Evidence:keywords)
KO assignmentNot mapped to KEGG
Loci Structure (Details)Loci index, Chromosomal location, Length, Possible relational loci clusterExon1: 209 residues, 110374401-110375027Exon2: 58 residues, 110375863-110376032Exon3: 78 residues, 110378215-110378443Exon4: 50 residues, 110379400-110379546Exon5: 20 residues, 110386848-110386902Exon6: 46 residues, 110392294-110392427Exon7: 63 residues, 110392744-110392929Exon8: 22 residues, 110407457-110407518Exon9: 53 residues, 110407899-110408052Exon10: 23 residues, 110408947-110409011Exon11: 103 residues, 110410662-110410967Exon12: 25 residues, 110431735-110431806Exon13: 38 residues, 110432077-110432185Exon14: 68 residues, 110432571-110432769Exon15: 63 residues, 110435543-110435726Exon16: 72 residues, 110438340-110438550Exon17: 61 residues, 110440435-110440614Exon18: 68 residues, 110442065-110442263Exon19: 32 residues, 110443068-110443160Exon20: 43 residues, 110447378-110447503Exon21: 52 residues, 110474466-110474617Exon22: 26 residues, 110475092-110475164Exon23: 22 residues, 110476344-110476404Exon24: 14 residues, 110478069-110478106Exon25: 299 residues, 110520970-110521863Exon26: 2 residues, -Jump to ATX2_HUMAN  
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Loci Cluster (Details)Loci: 4075 110566278-110608122 ~-42K 9715(BRAP)(-)Loci: 2788 110688728-110732165 ~-43K 9721(ALDH2)(+)Loci: 4074 110374401-110521863 ~-147K 9714(ATXN2)(-)Link out to UCSC