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0ARSI_HUMAN*   SwissProt (?) | Description Local Annotation Link Reference
General Information
NameARSI
DescriptionArylsulfatase i precursor (ec 3.1.6.-) (asi).
SpeciesHomo sapiens (NCBI taxonomy ID: 9606)
GON/A
Domain Architecture (Details)
InterPro domains unassigned to SynO:
Sulfatases () are enzymes that hydrolyze various sulphate esters. The sequence of different types of sulphatases are available and have shown to be structurally related .ncluding arylsulphatase A () (ASA). lysosomal enzyme which hydrolyzes cerebroside sulphate; arylsulphatase B () (ASB).hich hydrolyzes the sulphate ester group from N-acetylgalactosamine 4-sulphate residues of dermatan sulphate; arylsulphatase C (ASD) and E (ASE);steryl-sulphatase () (STS). membrane bound microsomal enzyme which hydrolyzes 3-beta-hydroxy steroid sulphates; iduronate 2-sulphatase precursor () (IDS). lysosomal enzyme that hydrolyzes the 2-sulphate groups from non-reducing-terminal iduronic acid residues in dermatan sulphate and heparan sulphate; N-acetylgalactosamine-6-sulphatase ().hich hydrolyzes the 6-sulphate groups of the N-acetyl-d-galactosamine 6-sulphate units of chondroitin sulphate and the D-galactose 6-sulphate units of keratan sulphate; glucosamine-6-sulphatase () (G6S).hich hydrolyzes the N-acetyl-D-glucosamine 6-sulphate units of heparan sulphate and keratan sulphate; N-sulphoglucosamine sulphohydrolase () (sulphamidase).he lysosomal enzyme that catalyzes the hydrolysis of N-sulpho-d-glucosamine into glucosamine and sulphate; sea urchin embryo arylsulphatase (); green algae arylsulphatase ().hich plays an important role in the mineralization of sulphates; and arylsulphatase () from Escherichia coli (aslA).lebsiella aerogenes (gene atsA) and Pseudomonas aeruginosa (gene atsA).
  IPR000917:Sulfatase
IPR000917:Sulfatase 
Evalue:-60.9208183288574 
Location:45-476
SequencesProtein: ARSI_HUMAN (569 aa)
mRNA: BC111002
Local Annotation
Synapse Ontology
Calcium release from RyR (Ryanodine Receptor) in the SR (Sarcoplasmic Reticulum) is activated by the calcium induced-calcium-release
sdb:0325 RyR-CICR  (Evidence:keywords)
KO assignmentNot mapped to KEGG
Loci Structure (Details)Loci index, Chromosomal location, Length, Possible relational loci clusterExon1: 756 residues, 149656101-149658368Exon2: 276 residues, 149661818-149662641Exon3: 2 residues, -Jump to ARSI_HUMAN  
Tune and view alternative isoforms
Loci Cluster (Details)Loci: 4743 149563423-149649529 ~-86K 29756(CAMK2A)(-)Loci: 4744 149656101-149662641 ~-7K 29760(ARSI)(-)Loci: 3502 149960834-150012089 ~-51K 29771(SYNPO)(+)Loci: 4745 150068502-150118769 ~-50K 29777(DCTN4)(-)Loci: 3501 149549712-149570827 ~-21K 29755(SLC6A7)(+)Link out to UCSC