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0AKAP6_HUMAN*   SwissProt (?) | Description Local Annotation Link Reference
General Information
NameAKAP6
DescriptionA-kinase anchor protein 6 (protein kinase a anchoring protein 6) (prka6) (a-kinase anchor protein 100 kda) (akap 100) (makap).
SpeciesHomo sapiens (NCBI taxonomy ID: 9606)
GO0005635 nuclear membrane (IDA)
0016529 sarcoplasmic reticulum (IDA)
0051018 protein kinase A binding (NAS)
0006605 protein targeting (NAS)

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schematic display of those terms with internal associations, click the node and browse the corresponding GO term
Domain Architecture (Details)
InterPro domains unassigned to SynO:
Spectrin repeats are found in several proteins involved incytoskeletal structure. These include spectrin.lpha-actininand dystrophin. The spectrin repeat forms athree helix bundle. The second helix is interrupted by prolinein some sequences. The repeats are defined by a characteristictryptophan (W) residue at position 17 in helix A and a leucine(L) at 2 residues from the carboxyl end of helix C.
  IPR002017:Spectrin repeat
IPR002017:Spectrin 
Evalue:-5.92081880569458 
Location:779-884IPR002017:Spectrin 
Evalue:-1.22914803028107 
Location:1078-1190IPR002173:PFKB_KINASES_2 
Evalue:0 
Location:2201-2214
SequencesProtein: AKAP6_HUMAN (2319 aa)
mRNA: NM_004274
Local Annotation
Synapse Ontology
transport of vesicles in the presynaptic neuron
sdb:0017 Mobilization: synapsins, CAM kinase I  (Evidence:keywords)
A dendritic spine is a mushroom-shaped bud that protrudes from a dendrite and forms one half of a synapse, especially in synapses of the cortex. The dendrites of cortical neurons typically are densely covered with such spines, which enable single cells to receive input from thousands of others.
sdb:0134 dendritic spine  (Evidence:keywords)
?
sdb:0265 cAMP mediated STP  (Evidence:keywords)
cytoskeleton filaments is one kind of structural components to maintain synapse morphology and bear the related function which is connected with the synaptic morphology.
sdb:0280 cytoskeletal filaments  (Evidence:keywords)
KO assignmentNot mapped to KEGG
Loci Structure (Details)Loci index, Chromosomal location, Length, Possible relational loci clusterExon1: 31 residues, 31868273-31868365Exon2: 121 residues, 31972416-31972774Exon3: 86 residues, 32074510-32074762Exon4: 592 residues, 32084186-32085956Exon5: 43 residues, 32116076-32116199Exon6: 34 residues, 32138366-32138463Exon7: 56 residues, 32139585-32139749Exon8: 51 residues, 32217267-32217416Exon9: 42 residues, 32234946-32235067Exon10: 51 residues, 32271410-32271557Exon11: 77 residues, 32274614-32274839Exon12: 74 residues, 32312634-32312850Exon13: 1140 residues, 32360358-32363772Exon14: 1073 residues, 32368804-32372018Exon15: 2 residues, -Jump to AKAP6_HUMAN  
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