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0AFG31_HUMAN*   SwissProt (?) | Description Local Annotation Link Reference
General Information
NameAFG3L1
DescriptionAfg3-like protein 1 (ec 3.4.24.-) (fragment).
SpeciesHomo sapiens (NCBI taxonomy ID: 9606)
GO0005739 mitochondrion (NAS)
0016887 ATPase activity (NAS)
0008237 metallopeptidase activity (NAS)

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schematic display of those terms with internal associations, click the node and browse the corresponding GO term
Domain Architecture (Details)
InterPro domains unassigned to SynO:
A large family of ATPases has been described whose key feature is that they share a conserved region of about 220 amino acids that contains an ATP-binding site. This family is now called AAA.or ATPases Associated with diverse cellular Activities. The proteins that belong to this family either contain one or two AAA domains.It is proposed that.n general.he AAA domains in these proteins act as ATP-dependent protein clamps .In addition to the ATP-binding A and B motifs (see the relevant entry ).hich are located in the N-terminal half of this domain.here is a highly conserved region located in the central part of the domain.
  IPR003959:AAA ATPase, central region
IPR003959:AAA 
Evalue:-16.8239078521729 
Location:1-69
SequencesProtein: AFG31_HUMAN (69 aa)
mRNA: BC021245
Local Annotation
Synapse Ontology
mitochondria are frequently observed in the vicinity of the synaptic vesicle clusters, in agreement with the ATP requirement of several steps of the vesicle cycle.
sdb:0118 mitochondria  (Evidence:keywords)
KO assignmentNot mapped to KEGG
Loci Structure (Details)Loci index, Chromosomal location, Length, Possible relational loci clusterExon1: 9 residues, 88572761-88572787Exon2: 33 residues, 88574150-88574245Exon3: 52 residues, 88575681-88575832Exon4: 25 residues, 88578439-88578508Exon5: 35 residues, 88582760-88582860Exon6: 48 residues, 88584774-88584912Exon7: 38 residues, 88586629-88586737Exon8: 44 residues, 88587676-88587802Exon9: 645 residues, 88588601-88590532Exon10: 2 residues, -Jump to AFG31_HUMAN  
Loci Cluster (Details)Loci: 4242 88238345-88251532 ~-13K 14727(PCOLN3)(-)Loci: 4243 88331459-88410566 ~-79K 14740(FANCA)(-)Loci: 2961 88512526-88514885 ~-2K 14748(MC1R)(+)Loci: 2962 88572761-88590532 ~-18K 14760(AFG3L1)(+)Loci: 2963 88616508-88638880 ~-22K 14764(GAS8)(+)Loci: 2960 88102305-88151674 ~-49K 14720(SPG7)(+)Link out to UCSC