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0ADML_HUMAN*   SwissProt (?) | Description Local Annotation Link Reference
General Information
NameADM
DescriptionAdm precursor .
SpeciesHomo sapiens (NCBI taxonomy ID: 9606)
GO0005615 extracellular space (TAS)
0005625 soluble fraction (TAS)
0005102 receptor binding (TAS)
0006171 cAMP biosynthesis (TAS)
0007267 cell-cell signaling (TAS)
0008015 circulation (TAS)
0007565 pregnancy (TAS)
0006701 progesterone biosynthesis (TAS)
0009611 response to wounding (TAS)
0007165 signal transduction (TAS)

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schematic display of those terms with internal associations, click the node and browse the corresponding GO term
Domain Architecture (Details)
InterPro domains unassigned to SynO:
Adrenomedullin is a hypotensive peptide.irst identified in human pheochromocytoma arising from adrenal medulla . The protein is ~185 amino acids in length.nd includes a 21-residue putative N-terminal signal sequence . The active peptide.hich is expressed in adrenal glands.ung.idney.eart.pleen.uodenum and submandibular glands.s thought to function as a hormone in circulation control.The adrenomedullin precursor is believed to contain 2 cleavage sites.ne of which produces the active adrenomedullin hormone.nd the other. 20-residue peptide (proadrenomedullin N-terminal 20 peptide.r proam-n20) of unknown function .
  IPR001710:Adrenomedullin
IPR001710:Adrenomedullin 
Evalue:-129.397933959961 
Location:21-185
SequencesProtein: ADML_HUMAN (185 aa)
mRNA: NM_001124
Local Annotation
Synapse Ontology
Calcium release from RyR (Ryanodine Receptor) in the SR (Sarcoplasmic Reticulum) is activated by the calcium induced-calcium-release
sdb:0325 RyR-CICR  (Evidence:keywords)
KO assignmentNot mapped to KEGG
Loci Structure (Details)Loci index, Chromosomal location, Length, Possible relational loci clusterExon1: 46 residues, 10283217-10283352Exon2: 41 residues, 10283802-10283921Exon3: 52 residues, 10284071-10284221Exon4: 350 residues, 10284454-10285499Exon5: 2 residues, -Jump to ADML_HUMAN  
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