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03BP5_HUMAN*   SwissProt (?) | Description Local Annotation Link Reference
General Information
NameSH3BP5
DescriptionSh3 domain-binding protein 5 (sh3 domain-binding protein that preferentially associates with btk).
SpeciesHomo sapiens (NCBI taxonomy ID: 9606)
GO0005737 cytoplasm (TAS)
0005515 protein binding (IPI)
0007165 signal transduction (TAS)

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schematic display of those terms with internal associations, click the node and browse the corresponding GO term
Domain Architecture (Details)
InterPro domains unassigned to SynO:
The SH3 domain-binding protein inhibits the auto and transphophorylation of BTK and acts as a negative regulator of BTK-related signalling in B cells.
  IPR007940:SH3-binding 5
IPR007940:SH3BP5 
Evalue:-155.920822143555 
Location:7-243
SequencesProtein: 3BP5_HUMAN (425 aa)
mRNA: NM_004844
Local Annotation
Synapse Ontology
mitochondria are frequently observed in the vicinity of the synaptic vesicle clusters, in agreement with the ATP requirement of several steps of the vesicle cycle.
sdb:0118 mitochondria  (Evidence:keywords)
KO assignmentNot mapped to KEGG
Loci Structure (Details)Loci index, Chromosomal location, Length, Possible relational loci clusterExon1: 522 residues, 15271249-15272814Exon2: 89 residues, 15273363-15273624Exon3: 75 residues, 15275341-15275561Exon4: 16 residues, 15276271-15276314Exon5: 45 residues, 15278669-15278800Exon6: 57 residues, 15286223-15286388Exon7: 45 residues, 15320613-15320742Exon8: 23 residues, 15347014-15347077Exon9: 111 residues, 15348781-15349108Exon10: 2 residues, -Jump to 3BP5_HUMAN  
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Loci Cluster (Details)Loci: 4589 15271249-15349108 ~-78K 25260(SH3BP5)(-)Loci: 3336 15443865-15459123 ~-15K 25264(EAF1)(+)Loci: 4590 15466644-15538262 ~-72K 25267(COLQ)(-)Loci: 4588 15086583-15115659 ~-29K 25257(ZFYVE20)(-)Link out to UCSC